Optilab™

Wyatt Technology’s Optilab™ and microOptilab™ are advanced on-line differential refractive index (dRI) detectors designed for precise concentration measurements in chromatographic separations. These instruments are essential for applications in high-performance liquid chromatography (HPLC), gel permeation chromatography (GPC), size-exclusion chromatography coupled with multi-angle light scattering (SEC-MALS), and field-flow fractionation (FFF-MALS).​

Optilab™: High-Performance dRI Detection for HPLC

The Optilab is a unique dRI detector for standard HPLC/GPC, offering 256 times the detection power and 50 times the dynamic range of conventional RI detectors. This exceptional performance makes it an invaluable component in any MALS setup, facilitating accurate concentration measurements across a wide range of solvents and analytes. ​

microOptilab™: Specialized dRI Detection for UHPLC

Tailored for ultra-high-performance liquid chromatography (UHPLC), the microOptilab brings the universal detection capabilities, unsurpassed concentration range, and superb sensitivity and linearity of the Optilab to the domain of UHPLC. Its compact design ensures minimal loss of resolution, making it an ideal companion for advanced UHPLC applications.

Key Features of Optilab™ and microOptilab™:

• Universal Detection: Both detectors operate independently of chromophores or fluorophores, allowing for the measurement of all sample types in virtually any solvent.​
• High Sensitivity and Dynamic Range: The Optilab offers 256 times the detection power and 50 times the dynamic range of conventional RI detectors, while the microOptilab provides high sensitivity and dynamic range suitable for UHPLC applications.
• Seamless Integration: Designed to integrate seamlessly with Wyatt’s MALS detectors, these dRI detectors enhance the accuracy and reliability of macromolecular analyses.​

Incorporating the Optilab or microOptilab into your chromatographic system enhances the precision and reliability of concentration measurements, leading to more accurate characterization of macromolecules and nanoparticles.​

For detailed specifications and additional information, please visit the official Wyatt Technology website.