iMScope™ QT

Next-Generation Mass Spectrometry Imaging with iMScope™ QT

Shimadzu introduces the iMScope™ QT, a revolutionary mass spectrometry imaging system that combines the analytical power of a high-resolution LCMS-Q-TOF with the visual clarity of an optical microscope. Building on the innovative concept of the iMScope series, this flagship instrument redefines MS imaging by delivering unmatched speed, sensitivity, and spatial resolution.

Total System for MS Imaging Analysis

The iMScope™ QT streamlines the entire MS imaging workflow into three key stages: sample pretreatment, data acquisition, and data analysis. At every stage, optimal techniques accelerate research while enhancing the reliability and depth of results.

Key Features and Benefits

• Fusion of Optical and MS Imaging: Exclusively from Shimadzu, the iMScope™ QT seamlessly overlays optical microscope images with mass spectrometry (MS) images. Whether capturing an entire sample area or focusing on detailed regions, this combined analysis provides a precise spatial correlation of morphological and chemical information.
• Exceptional Speed and High Spatial Resolution: With capabilities such as achieving 5 μm spatial resolution—as demonstrated in cerebellum imaging—the system captures detailed MS images rapidly. High-speed data acquisition minimizes analysis time while preserving sample integrity.
• Comprehensive Quantitative and Qualitative Analysis: The iMScope™ QT integrates LC-MS analysis with mass spectrometry imaging, enabling both distribution mapping and quantitative measurement in a single workflow. This dual functionality allows researchers to determine molecular concentrations and localize biochemical species accurately.
• Advanced Data Analysis and Composition Estimation: Powered by LabSolutions Insight™ software, users can perform robust data analysis. The LabSolutions Insight Explore™ function even enables the estimation of molecular formulas for unknown compounds, ensuring thorough characterization of complex samples.
• Revolutionary, High-Performance Operation: Following optical scanning, the sample plate is directly moved to the ionization position, initiating the imaging process without delay. This seamless transition enhances throughput and ensures precise, reproducible results.

Versatile Applications

The iMScope™ QT is ideally suited for a wide range of applications, including:

• Drug development and pharmaceutical research
• Tissue analysis and biomarker discovery
• Comprehensive studies in life sciences where detailed morphological and chemical data are critical

Experience a new era of mass spectrometry imaging that delivers rapid, high-resolution, and quantitative insights—integrated into a single, robust platform. For further information and detailed specifications, please visit the official Shimadzu website.