iMLayer™

Introducing the iMLayer™ Matrix Vapor Deposition System by Shimadzu

The iMLayer™ Matrix Vapor Deposition System is a cutting-edge sample pretreatment solution designed for MALDI-MS imaging. By utilizing an innovative vapor deposition method, the system creates fine matrix crystals that are essential for achieving high spatial resolution in MALDI-MS analyses. This advanced approach not only enhances the quality of imaging but also ensures that the matrix coating is applied with outstanding reproducibility.

Key Features:

• Fine Matrix Crystal Formation: The vapor deposition method produces finer matrix crystal grains, improving the overall quality of MALDI-MS imaging.
• Automated Coating Thickness Control: Thanks to fully automated control, users can configure and reproducibly maintain the optimal coating thickness, ensuring consistent matrix application across samples.
• User-Friendly Operation: A simple touch panel interface makes the system easy to operate, streamlining the sample pretreatment process.

Applications:

The iMLayer™ system is an essential tool for a wide range of MALDI-MS imaging applications. It has been successfully employed in projects such as:

• MS Imaging of Natural Toxins: For example, imaging natural toxin colchicine in autumn crocus bulbs using the iMScope™ QT.
• Visualization of Antimicrobial Substances: Imaging of the antimicrobial active substance scoparone in orange peel.
• Enzyme Histochemistry: Enabling detailed enzyme histochemistry studies using mass spectrometry imaging.
• Industrial Chemical Analysis: Evaluating applications of MS imaging in industrial chemical fields with methods like the dithranol deposition technique.
• Visualization of Biomolecules: Detailed imaging of phospholipids and glucose in rice koji using microscopic mass spectrometry imaging.

Enhance your MALDI-MS imaging workflow with the iMLayer™ Matrix Vapor Deposition System and achieve superior spatial resolution and reproducibility. For further information about its features and specifications, please visit the official Shimadzu website.